Alex Glennie (Kilmarnock Barassie) halved her morning foursomes match but lost in the singles in the afternoon.
(Report courtesy of the www.kirkwoodgolf.co.uk website)
The Scots, who had won their first two matches, shared the morning foursomes but lost the singles 4 1/2-1 1/2.
Only debutante Lelsey Loyd was a Scotland winner in the afternoon. Mary Smith secured a halved match.
ENGLAND SOUTH 6, SCOTLAND 3
Foursomes 1 1/2-1 1/2
J Rees and K Evans lost to S Wood and L Loyd 4 and 3.
C Weir and A Mayne bt F De Vries and A Ryan 4 and 3.
K Russell and D Richards halved with A Bartlett and A Glennie.
Singles 4 1/2-1 1/2
Rees bt Bartlett 4 and 2.
F Christine bt Wood 1 hole.
C Quinn halved with M Smith
Mayne lost to Lloyd 1 hole
Richards bt Glennie 3 and 2
Weir bt Ryan 2 and 1.
ENGLAND NORTH 5, ENGLAND MIDLANDS 4